I very recently re-deployed the Trac application on my server. The first time I did this, I used the included
tracd server, but I had a very hard time configuring it on a non-root path with Nginx. So I decided to use Gunicorn, which is also reported to give better performance (is it true? I did not test).
The configuration is a front-end server running Nginx coupled with a back-end server running Gunicorn + Trac and the database which will be PostgreSQL. Static files will be deported at the end to the front-end server for performance. I will not go too much into details in the process of installing the components, as they were packaged for the distribution I use (ArchLinux) and my environment did not need a strong separation into a virtual environment. So these steps are rather easy and better explained on the official website.